Despite never being nominated for Best Picture, Star Trek movies have attracted big-name Hollywood actors and have had several Oscar winners among their cast.

One Oscar-winning movie featured six actors from across the history of Star Trek, showcasing the franchise's enduring appeal to the world of acting talent.
Despite potential awards snubbery toward it, Star Trek remains a beloved institution that attracts many big-name Hollywood actors. For instance, Academy Award nominee Whoopi Goldberg had to convince her co-stars that she genuinely wanted to join the cast of Star Trek: The Next Generation. However, one Oscar-winning movie from the 1970s featured six different actors who would go on to play roles in Star Trek movies and shows throughout the 80s and 90s.
The 1975 Jack Nicholson movie One Flew Over the Cuckoo's Nest won five Academy Awards, including the Best Picture Oscar in 1976. It also featured six actors who would go on to play some big roles in the Star Trek franchise. Nurse Ratched was played by Louise Fletcher, who played Star Trek: Deep Space Nine's villainous Bajoran religious leader Kai Winn. One Flew Over the Cuckoo's Nest was also Brad Dourif's first credited movie role, and his powerful performance as Billy Bibbit earned him a nomination for Best Supporting Actor. Dourif would later play Star Trek: Voyager's most intriguing character, the Betazoid murderer, Lon Suder.
Other Star Trek actors who starred in One Flew Over the Cuckoo's Nest include Christopher Lloyd as Taber, Michael Berryman as Ellis, Vincent Schiavelli as the holographic arms dealer, and Peter Brocco as Colonel Matterson.
Louise Fletcher won numerous awards for her performance as Nurse Ratched in the film "One Flew Over the Cuckoo's Nest" in 1976, including an Academy Award, a BAFTA Award, and a Golden Globe Award. Despite this recognition, her name would only be featured in the awards ceremony once, and she went on to achieve further success with her roles in the television series "Star Trek: Deep Space Nine."
Michelle Yeoh is the only other Star Trek actress to win the Best Actress in a Leading Role Oscar.